Examining the Acute Effects of Two Different Fruit Juices (Orange Juice and Mixed Fruit Juice Consisted of Apple, Orange, Grape, and Pomegranate) on Postprandial Glycemic Responses and Satiety in Healthy Individuals
Overview
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Capillary blood glucose responses
Overview
Brief Summary
This study investigated the acute effects of two fruit juices on postprandial glycemic responses and satiety in healthy individuals
Detailed Description
This study aimed to 1. Determine the glycemic index and glycemic load of two types of fruit juices (orange juice and mixed fruit juice consisted of apple, orange, grape, and pomegranate) and 2. Investigate the effects of these two fruit juices on postprandial glycemic responses and satiety in healthy individuals
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Masking Description
Triple-blind
Eligibility Criteria
- Ages
- 18 Years to 55 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •non-smoking
- •non-diabetic and normotensive men and women
- •body mass index between 18.5 and 25 kg/m2
Exclusion Criteria
- •severe chronic disease (e.g. cardiovascular diseases, diabetes mellitus, kidney or liver conditions, endocrine conditions)
- •gastrointestinal disorders
- •pregnancy
- •lactation
- •competitive sports
- •alcohol abuse
- •drug dependency
Outcomes
Primary Outcomes
Capillary blood glucose responses
Time Frame: 2 hours
Clinically useful change in blood glucose, defined as the restoration of glucose within normal limits during the 2hr glucose tolerance test
Glycemic index
Time Frame: 2 hours
Glucose solution (50 g) was the reference food (GI = 100%) against which all test foods were compared. Subjects arrived at the laboratory at eight to nine o'clock in the morning after 10-12 h overnight fast. Each subject was fed equivalent 50 g available carbohydrate of test foods or reference food in random order. To minimize day to day variation of glucose tolerance, the reference food was tested in triplicate in each subject. All test and reference foods were served with 250 mL of water. An automatic lancet device and glucometer (calibrated MediSmart Ruby glucose meter with a lancing device, Lilly-PHARMASERV SA, Greece) was used for finger capillary blood samples. Blood samples were taken immediately before the start of the study (0 min) and 15, 30, 45, 60, 90 and 120 min after the start of eating.
Secondary Outcomes
- Blood pressure(2 hours)
- Subjective appetite ratings(2 hours)
Investigators
Aimilia Papakonstantinou
Assistant Professor
Agricultural University of Athens