Investigation of the Effectiveness of the Telerehabilitation Program in Patients With Liver Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- 6-Minute Walk Test
研究概览
简要总结
Liver transplantation is defined as a surgical procedure in which a liver with tissue damage and inability to perform its functions is replaced, in whole or in part, with a healthy liver obtained from a living or deceased donor. Post-transplantation treatment includes medical treatment, physiotherapy, and rehabilitation. Physiotherapy and rehabilitation, an important component of liver transplantation management, consists of three phases: preoperative, early postoperative, and late postoperative. Telerehabilitation is currently defined as the control or monitoring of rehabilitation remotely using telecommunication-related technologies. Studies on telerehabilitation in liver transplant patients are insufficient in the literature. The aim of this study is to investigate the effect of a telerehabilitation-based exercise program applied to liver transplant patients on exercise capacity, respiratory muscle strength, peripheral muscle strength, fatigue level and quality of life.
详细描述
Participants will be randomly divided into two groups: a telerehabilitation group and home exercise program group. Both groups will be evaluated before and after treatment (week 8). The telerehabilitation group will receive videoconference-based telerehabilitation three days a week for eight weeks. All exercises will be performed under the supervision of a physiotherapist. Each telerehabilitation session will last approximately 30-45 minutes. The exercises will be performed in the following order: breathing exercises, strengthening exercises, balance exercises, and walking exercises. The home exercise program group will receive an exercise brochure after the initial evaluation. Both groups will continue with their standard medical treatments, and a second evaluation will be conducted at the end of eight weeks. Participants' exercise capacity will be assessed using the "6-Minute Walk Test," fatigue level using "The Fatigue Severity Scale", respiratory muscle strength by measuring "Maximal inspiratory pressure (MIP)" and "Maximal expiratory pressure (MEP)", muscle strength using a digital dynamometer, balance using the "Timed Up and Go Test," and quality of life using the "The Liver Disease Symptom Index 2.0"
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Our study has two groups. The results will be evaluated by a blinded researcher who does not know which group they are assigned to.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being between 18-65 years of age and having undergone a liver transplant
- •Having had a liver transplant operation at least 6 months prior
- •Spontaneous breathing
- •Hemodynamic stability
- •Reading and writing skills
- •Ability to mobilize independently, ability to follow verbal and visual instructions
排除标准
- •Presence of unstable cardiovascular disease
- •Presence of primary lung disease requiring regular bronchodilator treatment
- •Presence of neuromuscular disease or neurological complications
- •Musculoskeletal limitation/use of assistive devices
- •Being a multiple organ transplant recipient
- •Presence of orthopedic disability and functional capacity limitation
研究组 & 干预措施
Telerehabilitation group
The telerehabilitation group will receive videoconference-based telerehabilitation three days a week for eight weeks. All exercises will be performed under the supervision of a physiotherapist.
干预措施: Telerehabilitation (Other)
Home exercise program group
Home exercise program group will initially be given instructions on the exercises and asked to perform them three days a week for eight weeks. They will be contacted by phone once a week to inquire whether they are doing the exercises.
干预措施: Home exercise (Other)
结局指标
主要结局
6-Minute Walk Test
时间窗: eight weeks
Exercise capacity will be assessed using the Six-Minute Walk Test, which plays an important role in evaluating pre- and post-operative exercise performance in liver transplant patients. The test will be conducted in a 30 m long, enclosed, straight corridor under the supervision of a physiotherapist, in accordance with the criteria set by the American Thoracic Society. The patients' heart rate and peripheral capillary oxygen saturation values will be recorded before, during, and after the test using a portable pulse oximeter. Dyspnea and perceived fatigue levels will be assessed using the Modified Borg Scale (MBS) during the test. The total walking distance completed in six minutes will be recorded in meters as the individual's six-minute walk distance
Timed Up and Go Test
时间窗: eight weeks
Used to evaluate the balance performance of individuals during movement. The person sits in a chair of standard height (46 cm), a distance of 3 meters is measured from the chair and a cone is placed at the end of this distance to indicate it. After receiving the command "walk as fast as you can and sit back down in the chair," the person gets up, walks down the corridor for meters, turns around, walks back to the chair and sits down. The time from the moment of getting up from the chair until the person turns around and sits back down in the chair is measured with a stopwatch and recorded in seconds.
次要结局
- The Liver Disease Symptom Index 2.0(eight weeks)
- The Fatigue Severity Scale(eight weeks)
- Respiratory Muscle Strength Measurement(eight weeks)
- Muscle Strength Measurement(eight weeks)
研究者
Alper AYAS
Lecturer
Istanbul University - Cerrahpasa