Effects of Laparoscopic Endometrioma Removal on Anti-mullerian Hormone Levels

Ankara University0 sites102 target enrollmentApril 2016

ConditionsEndometriosis Ovarian Reserve

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Endometriosis
Sponsor: Ankara University
Enrollment: 102
Primary Endpoint: Anti-Mullerian hormone levels
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue during surgery. Available evidence on the topic are contradictory and employed research methodology are diverse. There is need for an adequately powered research with proper methodology to assess actual effects of surgery.

Registry

clinicaltrials.gov

Start Date

April 2016

End Date

December 2018

Last Updated

10 years ago

Study Type

Observational

Sex

Female

Investigators

Sponsor

Ankara University

Responsible Party

Principal Investigator

Erkan Kalafat

Research Assistant

Ankara University

Eligibility Criteria

Inclusion Criteria

•Women with endometrioma cyst(s)
•Women of age under 35 years old
•Women without any previous ovarian surgery

Exclusion Criteria

•Combined oral contraceptive or long term GnRH (gonadotropin-releasing hormone) analog use in the preceding 3 months to enrolment
•Having another cystic lesion besides endometrioma
•Need for extensive bipolar coagulation during surgery
•Any anatomical problem preventing evaluation of ovaries with high-resolution ultrasound
•Postoperative pathology excluding endometrioma