Association Between Laparoscopic Removal of Endometriomas and Anti-mullerian Hormone Levels
- Conditions
- EndometriosisOvarian Reserve
- Interventions
- Procedure: Laparoscopic removal of cysts
- Registration Number
- NCT02685644
- Lead Sponsor
- Ankara University
- Brief Summary
Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue during surgery. Available evidence on the topic are contradictory and employed research methodology are diverse. There is need for an adequately powered research with proper methodology to assess actual effects of surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 102
Inclusion Criteria
- Women with endometrioma cyst(s)
- Women of age under 35 years old
- Women without any previous ovarian surgery
Exclusion Criteria
- Combined oral contraceptive or long term GnRH (gonadotropin-releasing hormone) analog use in the preceding 3 months to enrolment
- Having another cystic lesion besides endometrioma
- Need for extensive bipolar coagulation during surgery
- Any anatomical problem preventing evaluation of ovaries with high-resolution ultrasound
- Postoperative pathology excluding endometrioma
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Laparoscopic removal Laparoscopic removal of cysts Patients with endometrioma who will undergo laparoscopic removal of cysts.
- Primary Outcome Measures
Name Time Method Anti-Mullerian hormone levels 1 year AMH (anti-mullerian hormone) levels will be measured before surgery and during various time points up to 1 year after the surgery
- Secondary Outcome Measures
Name Time Method