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Clinical Trials/NCT02685644
NCT02685644UnknownNot Applicable

Effects of Laparoscopic Endometrioma Removal on Anti-mullerian Hormone Levels

Ankara University0 sites102 target enrollmentStarted: April 2016Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Enrollment
102
Primary Endpoint
Anti-Mullerian hormone levels
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue during surgery. Available evidence on the topic are contradictory and employed research methodology are diverse. There is need for an adequately powered research with proper methodology to assess actual effects of surgery.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 35 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Women with endometrioma cyst(s)
  • •Women of age under 35 years old
  • •Women without any previous ovarian surgery

Exclusion Criteria

  • •Combined oral contraceptive or long term GnRH (gonadotropin-releasing hormone) analog use in the preceding 3 months to enrolment
  • •Having another cystic lesion besides endometrioma
  • •Need for extensive bipolar coagulation during surgery
  • •Any anatomical problem preventing evaluation of ovaries with high-resolution ultrasound
  • •Postoperative pathology excluding endometrioma

Outcomes

Primary Outcomes

Anti-Mullerian hormone levels

Time Frame: 1 year

AMH (anti-mullerian hormone) levels will be measured before surgery and during various time points up to 1 year after the surgery

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Erkan Kalafat

Research Assistant

Ankara University

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