NCT02884024已完成不适用
Study on the Effects of Weight on Inflammation and Colon Cancer Risk
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 主要终点
- colonic concentration of Interleukin-6
研究概览
简要总结
An observational study designed to compare colonic cytokine concentrations in lean versus obese individuals
详细描述
An observational study was performed on 43 individuals undergoing routine screening colonoscopy, some of whom were lean and some who were obese. They had weight, height, and waist-hip ratio measured at the time of colonoscopy and had additional colonic biopsies to measure colonic cytokines.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •undergoing clinically-indicated screening colonoscopy
- •BMI< or = 25, or 30+
排除标准
- •past history of cancer (except non-melanoma skin cancer)
- •a polyposis syndrome
- •any current or chronic inflammatory disease or infection
- •incapable of providing valid informed consent
结局指标
主要结局
colonic concentration of Interleukin-6
时间窗: time zero: at baseline
colonic concentration of Interleukin-1 beta
时间窗: time zero: at baseline
colonic concentration of Interferon-gamma
时间窗: time zero: at baseline
colonic concentration of Tumor Necrosis Factor-alpha
时间窗: time zero: at baseline
次要结局
未报告次要终点
研究者
Joel Mason
Professor of Medicine and Nutrition
Tufts University
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