Comparison of the effect of eicosapentaenoic acid and docosahexaenoic acid on the treatment of depression

Research Accessory of Shahid Sadughi University of Medical Sciences0 个研究点目标入组 81 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•ages between 18-75 years; a Beck Depression Inventory II score of 10-28; a Hamilton Rating Scale for Depression score of 8-18; no changes in doses or types of antidepressant medications within 4 weeks prior to the study entry; diagnose of mild to moderate depression with structured clinical interview by a psychiatrist according to DSM-IV-TR criteria
•Exclusion criteria: diagnosis of any co-morbid mental disorder other than depression, serious suicidal or homicidal thoughts; use of fish oil or omega, supplements within the last 6 months or having taken more than 3 servings per weeks of fish; any changes in doses or types of current antidepressant medications within study period or use of psychotropics, anticonvulsants, mood stabilizers, and anticoagulants; cupping or blood coagulation disorders, gastrointestinal absorption disorders, and eating disorders; allergy to sea foods or study drugs, and history of multiple adverse drug reactions; history of electroconvulsive therapy or severe medical disorders that may lead in depression including cardiovascular, hepatic, renal, respiratory, and endocrine diseases; smoking and drug or alcohol abuse; pregnancy or breastfeeding; serious adverse effects and incompliance to study protocol

发起方

Research Accessory of Shahid Sadughi University of Medical Sciences