Collaborative Care in the Treatment of Depressive Disorder Containing an Antidepressant Algorithm and PST; a Multicentre Cluster Randomized Trial in Primary Care
Completed
- Conditions
- DepressionMajor Depressive Disorder
- Registration Number
- NL-OMON29861
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 240
Inclusion Criteria
A score of 15 or higher on the PHQ9, a short questionnaire that screens for Major Depressive Episode. The symptoms have to be present for at least six weeks, or have to cause marked dysfunctioning (for instance problems at work or sleeping problems).
Exclusion Criteria
Patients with high suicidal risk, those currently experiencing a psychotic episode, those who have dementia or those who are addicted to alcohol or narcotics are excluded from the study (they are however referred to the general practitioner in case of high suicide risk or a suggestion is given for another form of help).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Reduction of depressive symptoms remission.<br /><br>The severity of the symptoms is measured by the Inventory for Depressive<br /><br>Symptomatology-Self Report (IDS-SR) and the Patient Health Questionnaire<br /><br>depression subscale (PHQ9). The IDS-SR can be used for a global assessment of<br /><br>depressive symptoms. The instrument consists of 30 questions on a *0-3 scale*.<br /><br>The PHQ9 is a brief but valid instrument that scores each of the DSM-IV<br /><br>criteria from *0* (not at all) to *3* (nearly every day).<br /><br>Remission -reduction of DSM-IV criteria below threshold for a depressive<br /><br>disorder diagnosis [ref APA]- is measured by the MINI interview at the end of<br /><br>the intervention period (T1) and 12 months (T3), and with the PHQ9 -cut-off<br /><br>score below 15-. </p><br>
- Secondary Outcome Measures
Name Time Method