NL-OMON35587已完成2 期
Pain treatment of newborns: paracetamol rectal versus intraveneous administration, an open randomised clinical trial. - Pain treatment of newborns:paracetamol rectal versus iv administration
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 2 至 11（—）
入选标准
- •1. gestational age > 26 weeks
- •2. weight at birth for gestational age < p97
- •3. necessity for pain treatment (Comfortneoscore >/<= 14)
- •A minimum of 48 hours persistent pain treatment is required
排除标准
- •1. no necessity for pain treatment
- •2. macrosomia (weight at birth > p 97)
- •3. (severe) congenital abnormalities
- •4. less than 48 hours pain treatment is required
- •5. neonates are sedated or paralysed (Comfortneoscore impossible)
- •6. severe asphyxia (Apgar score < 4 after 5 minutes)
- •7. hepatic- and renal failure (at first blood screening)
- •8. rectal blood loss
- •9. necrotizing enterocolitis (active fase)
- •10. severe thrombocytopenia (< 50 x 10 9/l)
研究者
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