NL-OMON35587
已完成
2 期
Pain treatment of newborns: paracetamol rectal versus intraveneous administration, an open randomised clinical trial. - Pain treatment of newborns:paracetamol rectal versus iv administration
概览
- 阶段
- 2 期
- 干预措施
- 未指定
- 疾病 / 适应症
- pijn
- 发起方
- Vrije Universiteit Medisch Centrum
- 入组人数
- 24
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •1\. gestational age \> 26 weeks
- •2\. weight at birth for gestational age \< p97
- •3\. necessity for pain treatment (Comfortneoscore \>/\<\= 14\)
- •A minimum of 48 hours persistent pain treatment is required
排除标准
- •1\. no necessity for pain treatment
- •2\. macrosomia (weight at birth \> p 97\)
- •3\. (severe) congenital abnormalities
- •4\. less than 48 hours pain treatment is required
- •5\. neonates are sedated or paralysed (Comfortneoscore impossible)
- •6\. severe asphyxia (Apgar score \< 4 after 5 minutes)
- •7\. hepatic\- and renal failure (at first blood screening)
- •8\. rectal blood loss
- •9\. necrotizing enterocolitis (active fase)
- •10\. severe thrombocytopenia (\< 50 x 10 9/l)
结局指标
主要结局
未指定
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Pain treatment of newborns: paracetamol rectal versus intraveneous administration, an open randomised clinical trial. - Pain treatment of newborns: paracetamol rectal versus intraveneous administration.EUCTR2009-011753-41-NLeonatal intensive care unit, VU medical center Amsterdam
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