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Clinical Trials/ISRCTN81517281
ISRCTN81517281
Completed
未知

Randomized trial of different screening strategies for colorectal cancer

AIRC Scientific Directorate0 sites30,180 target enrollmentOctober 19, 2023

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
AIRC Scientific Directorate
Enrollment
30180
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

2005 Results article in https://pubmed.ncbi.nlm.nih.gov/15741571/ Results of the recruitment phase of the trial referring to the first phase of the study, which involved all centers. The data from the extended enrolment in Turin were not available yet for this analysis. (added 14/08/2023)

Registry
who.int
Start Date
October 19, 2023
End Date
December 31, 2016
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
AIRC Scientific Directorate

Eligibility Criteria

Inclusion Criteria

  • In Turin and Milan, the target population included all patients aged 55 – 64 years who were listed in the rosters of a random sample of general practitioners who had not been involved in a previous trial (SCORE ISRCTN27814061 of 08/12/2010\).
  • In the other centers, the target population was recruited from those districts not yet involved in the SCORE trial (Biella and Rimini) or in the ongoing regional colorectal cancer screening program (Florence). All residents aged 55 – 64 years in those districts were targeted for recruitment: the researchers identified and contacted their general practitioners, who were invited to collaborate in the study.
  • In all centers, GPs were asked to review the list of their patients targeted for recruitment to exclude subjects not eligible for the trial.

Exclusion Criteria

  • 1\. Unable to give informed consent
  • 2\. Diagnosed with a terminal illness or inflammatory bowel disease
  • 3\. History of polyps or colorectal cancer or two first\-degree relatives with colorectal cancer
  • 4\. Undergone a colorectal endoscopy or a FOBT within the previous 2 years
  • 5\. Already included in a previous trial (SCORE ISRCTN27814061 \- 08/12/2010\) and had changed their general practitioner to one that was included in this study or who had moved to a district included in the current study area

Outcomes

Primary Outcomes

Not specified

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