NCT02305043已完成不适用
Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Adenocarcinoma of the Stomach or Gastroesophageal Junction. A Non-interventional Study
University of Leipzig1 个研究点 分布在 1 个国家目标入组 549 人开始时间: 2014年3月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 549
- 试验地点
- 1
- 主要终点
- Percentage of Participants With Objective Response
研究概览
简要总结
The aim of this study is to identify biomarkers predicting response or resistance factors of a targeted therapy with trastuzumab in advanced gastric cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •histologically proven adenocarcinoma of the stomach or gastroesophageal junction
- •patient receives chemotherapy
- •signed informed consent
- •Age > 18 years
排除标准
- •Patient can not understand meaning and purpose of the study
- •patient already received a chemotherapy treatment for advanced disease.
结局指标
主要结局
Percentage of Participants With Objective Response
时间窗: 12 months
Percentage of participants with objective response based assessment of confirmed complete response (CR) or confirmed partial response (PR). CR is defined as the disappearance of all target lesions. PR is defined as at least 30% decrease in the sum of the longest dimension of the target lesion
次要结局
- time-to-progression(up to 24 months)
- overall survival(up to 24 months)
研究者
Florian Lordick, MD
Director University Cancer Center Leipzig
University of Leipzig
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Investigation of biomarkers for predicting the response to steroids in patients with COPDCOPDJPRN-UMIN000010711Third Department of Internal Medicine, Wakayama Medical University80
进行中（未招募）
1 期
prediction of response to therapy in inflammatory bowel diseaseEUCTR2018-002925-47-ESFundación de Investigación Biomédica del Hospital Universitario de La Princesa180
招募中
不适用
Biomarkers in Retinitis PigmentosaRetinitis PigmentosaNCT06306690Fondazione Policlinico Universitario Agostino Gemelli IRCCS35
已完成
不适用
Identification of biomarkers that predict responsiveness to Dupilumab among severe asthmaasthmaJPRN-UMIN000041915ational Hospital Organization Tokyo National Hospital15
Unknown
不适用
Development of Biomarker for the Evaluation of Response After Neoadjuvant Therapy in Patients With Pancreatic CancerGenetic ChangeChemotherapy EffectPancreatic CancerNCT04110769Asan Medical Center10