An investigation on spinal fluid in patients with sciatica-type or nerve-type pain of the lower limb

Not Applicable

Completed

• Conditions: Nervous System Diseases; europathic lower limb pain

• Registration Number: ISRCTN34007592
• Lead Sponsor: Trinity Translational Medicine Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-04
• Study Completion: 2023-07-31
• Last Update Posted: 28 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

1. Chronic radicular pain
2. Scheduled to undergo pulsed radiofrequency treatment (PRF).

Exclusion Criteria

Coagulopathy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of PD-1 and PD-L1 in the patients spinal fluid (as quantified by flow cytometry)

Secondary Outcome Measures

Name	Time	Method
Change in pain score of patient at 3 month interview and use of Douleur Neuropathique pain questionnaire at baseline (day of procedure) and 3 months later (when back in clinic)