Effect of socket filling material on free gingival graft survival in alveolar ridge preservation: A randomized controlled trial

Phase 1

Completed

• Conditions: Socket type l and ll of Elian classification, anterior and premolar tooth; Socket type l and ll of Elian classification; Tooth derived bone graft materials; Alveolar ridge preservation; Palatal gingival graft; Free gingival graft; Allograft

• Registration Number: TCTR20210104001
• Lead Sponsor: Ministry of Higher Education, Science, Research and Innovation, Prince of Songkla University

Brief Summary

The viability of a free gingival graft used as a socket sealing on the socket orifice remained unaffected by the graft material within the socket. Notably, the vitality score of the free gingival graft on day 7 holds a positive correlation for the subsequent alterations in the alveolar ridge after socket sealing with FGG. Regarding the alveolar bone alteration, in socket graft with different grafting material, slow resorption material tends to be the most effective in maintaining ridge volume.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-04
• Study Completion: 2023-08-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 41

Inclusion Criteria

1.Adults patients (> 20 years old).
2.Residual extraction sockets of one upper or lower anterior and premolar tooth in Elian socket classification type l and ll.
2.The patient can sign the consent form to participate in the study and able to follow up on the appointment.
3.Presence of adjacent (mesial and/or distal) tooth at the extraction site.
4.Systemically healthy patients and cessation of smoking for 1 week before treatment.
5.No contraindication for minor oral surgery.

Exclusion Criteria

1.Patients with a history of malignancy radiotherapy or chemotherapy for treatment of malignancy.
2.Pregnant patient or intending to become pregnant or nursing at the time of study inclusion.
3.Patients taking medications or having treatments with an effect on healing in general eg. steroids, large doses of anti-inflammatory drugs and bisphosphonates.
4.Patients have an active infection in the area of study.
5.Patients have severe periodontal disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival rate of free gingival graft Immediately, 3 days, 1 week, 2 weeks, 1 month Clinical photograph

Secondary Outcome Measures

Name	Time	Method
Clinical volume of alveolar ridge Immediately, 1 and, 3 months after ARP cubic millimeter,Vertical alveolar bone alteration Immediately and 3 months after ARP millimeter,Horizontal alveolar bone alteration Immediately and 3 months after ARP millimeter,Mineralized tissue volume changes Immediately and 3 months after ARP cubic millimeter