Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment

Not Applicable

Completed

• Conditions: Iron-deficiency
• Interventions: Diagnostic Test: Blood sampling

• Registration Number: NCT05514951
• Lead Sponsor: Vifor Pharma

Brief Summary

Iron deficiency is defined by insufficient tissue iron stores and anemia is the ultimate stage of iron deficiency. Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

Detailed Description

Iron deficiency (MD) is defined by insufficient tissue iron stores. Since iron is essential for the synthesis of hemoglobin, when the iron deficiency no longer makes it possible to maintain a sufficient level of erythropoiesis, anemia appears: it is the ultimate stage of iron deficiency.

Anemia is the most common haematological pathology encountered in geriatric practice. Its prevalence, in population generally ambulatory, is between 10 and 15% after the age of 65 and is greater than 20% beyond the age of 85.

Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications heart disease, cognitive decline, frailty, hospitalizations, and impairment of quality of life. About a third of anemias elderly person is attributable to a deficiency in vitamin B9 or B12 or an iron deficiency.

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic such as heart failure, kidney failure chronic or cancer, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

This diagnosis is all the more important because, depending on the chronic pathology, data from the literature have shown that correcting the iron deficiency brings benefits to the patient by reducing the risk of recurrence of anemia, the prescription of erythropoietin and the use of transfusion for patients in oncology, gastroenterology and nephrology

Study Timeline

• Study First Submitted: 2022-08-22
• Study First Submitted QC: 2022-08-22
• Study First Posted: 2022-08-25
• Study Start: 2022-11-15
• Primary Completion: 2022-12-09
• Study Completion: 2022-12-09
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-24
• Last Update Posted: 2025-03-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 888

Inclusion Criteria

• Any patient hospitalized in a geriatric unit (short geriatric stay, SSR) or seen on an outpatient basis (hospitalization day, consultation)
• Affiliated patient or beneficiary of a social healthcare system
• Patient having given written consent

Exclusion Criteria

• Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by court order or administration

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Blood sampling	Blood sampling	Blood sampling

Primary Outcome Measures

Name	Time	Method
Percentage of patients diagnosed with iron deficiency on inclusion	Day 1	The diagnosis of iron deficiency will be made from the measurements of the ferritinemia and CST: Ferritinemia \< 100 µg/L and/or CST \< 20%

Trial Locations

Locations (16)

Chu Angers; 🇫🇷 ANGERS Cedex 9, France

CH Chambéry; 🇫🇷 Chambéry, France

CH de Bayonne; 🇫🇷 Bayonne, France

Hôpital Gériatrique Les Bateliers Chu Lille; 🇫🇷 Lille Cedex, France

Chu De Nantes, Hôpital Bellier; 🇫🇷 Nantes Cedex 1, France

CHU de NICE-hopital CIMIEZ; 🇫🇷 Nice, France

Hopital Saint Antoine; 🇫🇷 Paris Cedex 12, France

Ch De Calais; 🇫🇷 Calais Cedex, France

Ch de Dunkerque; 🇫🇷 Dunkerque Cedex 1, France

CHSF; 🇫🇷 Corbeil-Essonnes, France

CH de Pau; 🇫🇷 Pau, France

CHU de Poitiers; 🇫🇷 Poitiers, France

HUS - Hôpitaux Universitaires de Starsbourg; 🇫🇷 Strasbourg, France

Hôpital Bretonneau; 🇫🇷 Tours Cedex 9, France

Chu Nancy; 🇫🇷 Vandoeuvre-Lès-Nancy, France

HCL; 🇫🇷 Villeurbanne, France