Effect of Tacrolimus drop in Nasal Polyp Recurrence
Not Applicable
Recruiting
- Conditions
- Condition 1: Nasal polyps. Condition 2: Chronic rhino sinusitis.Polyp of nasal cavityChronic sinusitis, unspecifiedJ33.0J32.9
- Registration Number
- IRCT20221206056721N1
- Lead Sponsor
- Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Patients referred to Shafa Kerman Hospital in 1401 who are candidates for surgery due to chronic rhinosinusitis with polyps (patients who have not responded to common treatments including broad-spectrum antibiotics, inhaled steroids, and short-term courses of oral steroids)
Informed consent to enter the study
Exclusion Criteria
Age less than 18 years
Suffering from genetic diseases including Ciliary Dyskinesia or Cystic Fibrosis
Recurrence of polyps less than 3 months after surgery
Patients who were in the intervention group and showed sensitivity to tacrolimus drops.
Patients who did not refer for follow-up
Lack of informed consent to enter the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method und-Kennedy Score. Timepoint: Patients of both groups were followed up at intervals of 3 months, 6 months, and 9 months after surgery, and the Lund-Kennedy score was calculated during endoscopic examination. Method of measurement: Method of measurement: endoscopy and unit of measurement: score.
- Secondary Outcome Measures
Name Time Method und-Mckay score. Timepoint: Patients of both groups underwent follow-up at intervals of 3 months, 6 months, and 9 months after surgery. Method of measurement: Method of measurement: CT Scan and unit of measurement: score.