Myotonic Dystrophy, PrOteiN and Diet study. Part 1. - MD-POuND

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年4月15日

试验速览

暂无简介。

•- Implantation of pacemaker or ICD device, a implantable insulin device, a
•neurostimulator, internal hearing aid or artificial heart valve.
•- Implantation of orthopaedic prostheses, screws or plates.
•- Metal shreds or splinters inside the body.
•- Vascular clips in the body.
•- Big tattoo*s and/or permanent make-up.
•- Claustrophobia.
•- Use of medication interacting with muscle metabolism (such as steroids and
•- Diabetes mellitus.
•- Weight loss of more than 3 kg in the last three months.
•- Pregnant or lactating women.
•- Use of protein supplements.
•- Participation in an exercise program.
•- Patients who are not able to perform basic activities of daily living such as
•walking or patients who are suffering from other disabling comorbidity that
•seriously hamper physical exercise (e.g. heart failure, coronary artery
•disease, chronic obstructive pulmonary disease (COPD), orthopedic conditions).
•- Body mass index (BMI) <18 or >35.
•- Use of oral anticoagulants.
•- In case of DM1 affected subjects: muscular impairment rating scale (MIRS)
•score of 5 (which represents severe proximal muscle weakness).
•- In case of the healthy control group: presence of a neuromuscular disorder or
•an abnormal neurological examination (specifically if muscle weakness is
•present), or other condition possibly interfering with muscle strength or
•muscle mass.

发起方

Medisch Universitair Ziekenhuis Maastricht