试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48,850
- 主要终点
- Colorectal Cancer
研究概览
简要总结
The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors. A second questionnaire was sent out in 2008-09.
详细描述
The Cohort of Swedish Men was established in 1997, when all men born between 1918 and 1952 and residing in Västmanland and Örebro counties in central Sweden received a questionnaire concerning diet and other lifestyle factors. Of the 100,303 eligible men, 48,850 (49%) responded to the questionnaire. The questionnaire included items about diet, physical activity, medical history, and lifestyle factors such as cigarette smoking history and use of dietary supplements.
During 2008-09, the exposure information was updated and extended by sending out two new questionnaires - one questionnaire on health including several signs of symptoms, sleeping, social relations etc (2008) and one on diet, dietary supplement use, and lifestyle factors (2009). Majority of questions in the questionnaires have been validated.
Incident cases of cancer are ascertained by record linkages of the study population with the National Swedish Cancer Register and the Regional Cancer Registers. Cardiovascular and other diseases as well as surgeries and causes of death are identified by linkage to the National Inpatient and other registries at the Swedish Board of Health and Welfare. Ascertainment of cancer cases and other diseases is almost 100% complete. Dates of deaths are ascertained through the Swedish Death Register (100% complete), and information on date of moving out of the study area is obtained by linkage with the Swedish Population Register.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 79 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •All men born between 1918 and 1952, living in central Sweden
排除标准
- 未提供
结局指标
主要结局
Colorectal Cancer
时间窗: 1997-2010
Prostate cancer
时间窗: 1997-2010
Pancreatic cancer
时间窗: 1997-2010
Stomach cancer
时间窗: 1997-2010
Bladder cancer
时间窗: 1997-2010
Fractures, hip fractures
时间窗: 1997-2014
Cataract
时间窗: 1997-2010
LUTS (Lower urinary tract symptom)
时间窗: 1997-2010
Cardiovascular Diseases
时间窗: 1997-2010
Mortality
时间窗: 1997-2010
次要结局
未报告次要终点
研究者
Alicja Wolk
Professor
Karolinska Institutet
