Evaluation of Dry Eye and Meibomian Gland Dysfunction After Cataract Surgery
Completed
- Conditions
- Meibomian Gland Dysfunction
- Registration Number
- NCT01942642
- Lead Sponsor
- Yonsei University
- Brief Summary
Meibomian gland dysfunction (MGD) is a common and important disease has been investigated the pathophysiology, diagnosis, treatment modalities of MGD, however, the changes of MGD after the cataract surgery, the most popular surgery to ophthalmologist, had not been evaluated. The investigators evaluated parameters related with MGD including lid margin abnormalities, meibomian gland expressibility and meibography before and after surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
- Patients scheduled for cataract surgery
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Exclusion Criteria
- other comorbid ocular diseases such as ocular allergies.
- continuous use of topical ocular medications before surgery
- histories of ocular surgery, or ocular injury
- Already had severe obstructive MGD before surgery, abnormal findings on lid margin (> 3 positive findings), reduced meibum expression (> grade 2), and obstructed gland dropout (meibography score > 3)
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ocular parameters change of Ocular parameters from 1 to 3 months after cataract surgery Ocular symptom score, lid margin abnormalities, superficial punctuate keratopathy, tear film break-up time, Shirmer's test, lower tear meniscus height (TMH), depth (TMD), and area (TMA), meibum expressibility, and meibography score
- Secondary Outcome Measures
Name Time Method