NL-OMON30945招募中不适用
Circulating blood cell populations in pateints with Diabetes mellitus and coronary artery disease: studies on cellular functions - VERAD2B
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 136
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Diabetes mellitus: Diabetes type II, compensated with diet and/or oral medication.
- •CAD: History of coronary artery disease >2 years, no myocardial infarction in the last 6 months.
- •AMI: >3-fold increase of CK (CK-MB) levels. Patients with coronary artery disease in their early period after Acute Myocardial Infarction (day 4 - 7 post-infarction) will be recruited.
- •Controls: patients diagnosed with hypertension, arrhythmias and/or heart valvular diseases; subjects should be age-matched with the above mentioned groups (subjects <45 years or >75 years old will be excluded).
排除标准
- •Anemia (Hb<8 g/L)
- •Acute infectious diseases (e.g., pneumonia, urinary tract infections, anaphylactic shock etc.)
- •Acute inflammation other than AMI (elevated leukocyte number)
- •Acute conditions (surgery, stroke, thromboembolism etc)
- •Single or multiorgan failure (heart failure NYHA III/IV, lung, liver, kidneys)
- •Chronic inflammatory diseases (chronic kidney diseases, rheumatoid arthritis)
- •Malignant diseases (or recent history of malignant diseases <1 year)
- •Malignant arterial hypertension
- •Hormonal treatment (thyroid hormones-T3/T4 not included) or anti-inflammatory drugs
- •Genetic disorders (Down syndrome, X&Y chromosome syndrome), family hypercholesterolemia, genetic dyslipidemia
- •Psychiatric abnormalities
研究者
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