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Clinical Trials/NCT05087836
NCT05087836
Completed
Not Applicable

Correlation of Regional Cerebral Oxygen Saturation Monitoring by NIRS Between Standard Site vs Alternative Sites of Sensor Position in Adult Cardiac Surgery

Khon Kaen University1 site in 1 country21 target enrollmentNovember 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebral Ischemia
Sponsor
Khon Kaen University
Enrollment
21
Locations
1
Primary Endpoint
rScO2
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Cardiac surgery and neurosurgery may decrease cerebral blood flow leading to cerebral dysfunction. Regional cerebral oxygen saturation (rScO2) monitor via Near-infrared spectometry (NIRS) is recommended for early detection and correction. The standard site of NIRS sensor is forehead area which is impractical in operation with incision at forehead area. The investigators suggest an alternative sensor site at temporal area. The objective of this study is to assess the correlation of rScO2 measured from sensor attached at forehead vs. temporal area.

Detailed Description

Cardiac surgery and neurosurgery may decrease cerebral blood flow leading to neurologic morbidity, e.g., postoperative stroke, delirium, or postoperative cognitive dysfunction. Regional cerebral oxygen saturation (rScO2) monitor via Near-infrared spectometry (NIRS) is thus recommended for early detection and correction. Murkin et al.(2007) conducted a randomized controlled trial in coronary artery bypass graft (CABG) with NIRS monitoring showed that patients who received intervention to avoid rScO2 \< 75% of baseline had less major organ morbidity including stroke, and mortality. Senanayake et al.(2012) revealed that NIRS could decrease neurologic complication in patients undergoing ascending aortic replacement with moderate hypothermic circulatory arrest. The standard site of NIRS sensor is forehead area. There are some types of surgery involving incision at forehead area which makes it not possible to attach sensor at this site. The investigators propose an alternative sensor site at temporal area to be used in such situation. The objective of this study is to assess the correlation of rScO2 measured from sensor attached at forehead vs. temporal area.

Registry
clinicaltrials.gov
Start Date
November 1, 2021
End Date
March 10, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Thepakorn Sathitkarnmanee

Associate professor

Khon Kaen University

Eligibility Criteria

Inclusion Criteria

  • age =/\> 18 y
  • undergoing elective cardiac surgery
  • American Society of Anesthesiologists (ASA) classification II-III

Exclusion Criteria

  • history of intracranial or carotid vascular disease
  • previous surgery at face or brain
  • abnormal anatomy of face
  • re-do surgery

Outcomes

Primary Outcomes

rScO2

Time Frame: intraoperatively

Regional cerebral oxygen saturation

Study Sites (1)

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