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临床试验/NCT05097664
NCT05097664Unknown不适用

Ocular Manifestation and Related Risk Factors of Covid-19 Associated Mucormycosis: a Multicenter Study in Iran

Isfahan University of Medical Sciences1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2021年8月23日最近更新:
适应症

试验速览

阶段
不适用
入组人数
250
试验地点
1
主要终点
Vision loss

研究概览

简要总结

Coronavirus disease 2019 (COVID-19) infection caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may manifest as a variety of disease patterns, ranging from mild to life-threatening pneumonia.

Mucormycosis has been suspected to cause significant morbidity in infected people since the outbreak of the COVID-19 pandemic. Individuals who require hospitalization and intensive care are more vulnerable, as they have reached an advanced stage of their disease. Investigators will discuss the major risk factors, ocular presentation, and outcome of mucormycosis in individuals infected with SARS-CoV-2 in this study. From August 2021 to January 2022, a cross-sectional descriptive multicenter investigation would be conducted on patients with biopsy-confirmed mucormycosis and RTPCR confirmed COVID19. Demographic data, the time interval between COVID19 and mucormycosis, underlying systemic disorders, clinical characteristics, disease course, and outcomes would be analyzed.

详细描述

Investigators will achieved the following data from the participants:

  1. Demographic
  2. Past medical/habitual history
  3. COVID-19 status and related risk factors
  4. Mucormycosis status and related risk factors
  5. Ocular examination and imaging
  6. Follow-up

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Diagnosed case of Mucormycosis in COVID-19 pandemic

排除标准

  • People with acute or severely ill conditions that prevent them from ophthalmic examination.
  • Patient, or legal representative opposing the pursuit of the research

结局指标

主要结局

Vision loss

时间窗: 3 months

Prevalence of Vision loss in COVID-19 patients with Mucormycosis co-infection

次要结局

  • Risk factors(3 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohsen Pourazizi

Dr. Mohsen Pourazizi

Isfahan University of Medical Sciences

研究点 (1)

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