NL-OMON31453招募中4 期
iver toxicity of azathioprine and 6-mercaptopurine in IBD patients. - Liver toxicity of azathioprine and 6-mercaptopurine
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational invasive
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •IBD patients
- •18 years or older
- •who have been treated at least 5 years with azathioprine and/or 6-mercaptopurine
- •who give permission for ultrasound guided liverbiopsy and MRI
排除标准
- •anaemia (Hb < 6.5 mmol/L), thrombocytopenia (Thr < 50 * 10 9/L), prolonged INR (INR > 1.5), ascites.
- •exclusioncriteria for MRI: pacemaker, ICD, metal intracerebral clips, known allergy for contrast agents that are used, claustrophobia.
研究者
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