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study on Amukkara Chooranam for the management of mudakku vatham

Not Applicable
Completed
Conditions
Health Condition 1: M259- Joint disorder, unspecifiedHealth Condition 2: null- Patients having the symptoms ofRheumatoid Arthritis
Registration Number
CTRI/2017/02/007887
Lead Sponsor
Dr A Mariappan
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
19
Inclusion Criteria

Symmetrical joint involvement

Arthritis of three or more joints

RA factor positive or negative

Morning stiffness

Deformities like swan neck deformity and button hole deformity

Swelling especially in the inter-phalangeal

joint

Exclusion Criteria

Pregnancy and lactation

Tubercular arthritis

Any other serious systemic illness

Osteoarthritis

Psoriatic arthritis

Gouty arthritis

Diabetes mellitus

Hypertension

Hyperlipidemia

Cardiac diseases

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the therapeutic efficacy of siddha drug Amukkura chooranam in reducing the pain and restricted joint movements in the treatment of rheumatoid arthritisTimepoint: At the end of the treatment
Secondary Outcome Measures
NameTimeMethod
To study the siddha basic principles like Envagai thervu,Neerkuri and Neikuri,Udalthathukal,Uyirthathukal and Kaalam etc.,in Uthira vatha suronitham patients. <br/ ><br>To study the effect of Amukkura chooranam on levels of IL-1,IL-6,IL-10,IL-12,IL-4,IL-17,IL-23 and TNF-alfa in blood of Uthira vatha suronitham patients and thereby to elicit possible mechanism of action of the Amukkura chhooranam.Timepoint: At the end of the treatment
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