MedPath

Comparison of Intracorporeal and Extracorporeal Anastomoses for Minimally Invasive Right Colectomy

Completed
Conditions
Crohn Disease
Colonic Neoplasms
Interventions
Procedure: Right Colectomy
Registration Number
NCT03019016
Lead Sponsor
Intuitive Surgical
Brief Summary

The primary objective of this study is to retrospectively compare the perioperative and short-term (discharge through 30 days) outcomes of intracorporeal and extracorporeal anastomosis in minimally invasive right colectomies for benign and malignant disease.

The secondary objective of this study is to retrospectively compare the rates of incisional hernia (up to 6 month post procedure) between intracorporeal and extracorporeal arms.

Detailed Description

This is a multi-center, retrospective chart review study of all consecutive cases of right colectomy performed by participating surgeons at their respective institutions that meet all inclusion and exclusion criteria. All cases of right colectomy performed with intracorporeal or extracorporeal anastomoses or via laparoscopic or robotic platforms that meet the study inclusion and exclusion criteria, will be considered for inclusion. The chart review will be performed in a reverse chronological order starting at a minimum of 30 days prior to IRB approval of the study at the site until the number of robotic-assisted and laparoscopic cases to be included per surgeon has been met. Study initiation at the participating site will occur once a research agreement has been executed between Intuitive Surgical and the participating Institution/Investigator and IRB approval has been obtained.

It is anticipated that the retrospective chart review will span the period between January 1, 2010 through 30-days prior to IRB approval of the study in 2016. Baseline patient characteristics, perioperative and post-operative short term clinical and pathological outcomes, and incisional hernia data will be obtained from hospital records for a total of up to approximately 1000 robotic and laparoscopic cases, among the 4 subgroups: robotic-assisted right colectomy with intracorporeal anastomosis (RRCIA), robotic-assisted right colectomy with extracorporeal anastomosis (RRCEA), laparoscopic right colectomy with intracorporeal anastomosis (LRCIA) and laparoscopic right colectomy with extracorporeal anastomosis (RRCEA). Since the data will have been de-identified, and is archival in nature, there will be no active subject recruitment.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1000
Inclusion Criteria
  • Age ≥ 18 years
  • Patients with benign or malignant right colon disease
  • Patients who have undergone robotic-assisted or laparoscopic right colectomy with intracorporeal or extracorporeal anastomosis either on or proximal to mid-transverse colon
Read More
Exclusion Criteria
  • Patients with perforated, obstructing or locally invasive neoplasm (T4b)
  • Emergency procedures
  • Patients undergoing right colectomy as a secondary procedure
  • Patients undergoing radiation therapy for malignant neoplasia before and after procedure
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Robotic RC (IA)Right ColectomyBenign or malignant disease under going a right colectomy.
Laparoscopic RC (IA)Right ColectomyPatients with benign or malignant disease under going a right colectomy.
Laparoscopic RC (EA)Right ColectomyPatients with benign or malignant disease under going a right colectomy.
Robotic RC (EA)Right ColectomyPatients with benign or malignant disease under going a right colectomy.
Primary Outcome Measures
NameTimeMethod
Chart review on PeriOperative InformationIntraoperative through 30-days follow-up

Number of complications observed intraoperatively through 30-days

Secondary Outcome Measures
NameTimeMethod
Chart review on Postoperative InformationPostoperative through 6 month follow-up

Number of complications observed postoperatively through 6 month

© Copyright 2025. All Rights Reserved by MedPath