Investigating the effect of adding L-carnitine supplement to migraine prophylaxis treatment

Phase 3

Recruiting

• Conditions: Migraine.; Migraine, unspecified; G43.9

• Registration Number: IRCT20200418047116N3
• Lead Sponsor: Gonabad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Signed informed consent
Migraine with or without aura according to the International Classification of Headache Disorders
Having 2 or more migraine attacks per month during the past 3 months
Migraine onset before age 50
BMI (kg/m2) between 18 and 35

Exclusion Criteria

Absence of kidney disease or reduced kidney function and liver cirrhosis
No previous use of L-carnitine
No use of = 3 prophylactic medications against migraine during the past 5 years
No alcohol or illegal drug addiction
Not having asthma or vascular disease, arterial lameness
Pregnancy, breastfeeding

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of days with moderate to severe headache lasting more than 4 hours or treated with usual treatments. Timepoint: Before the intervention and 4 and 8 weeks after the intervention. Method of measurement: check list.

Secondary Outcome Measures

Name	Time	Method
umber of days with migraine. Timepoint: Before the intervention and 4 and 8 weeks after the intervention. Method of measurement: check list.;Severity of headache on days with headache. Timepoint: Before the intervention and 4 and 8 weeks after the intervention. Method of measurement: MIGSEV scale.;Doses of analgesics and triptans. Timepoint: Before the intervention and 4 and 8 weeks after the intervention. Method of measurement: check list.