Fentanyl Test in Children's Adenotonsillectomy
- Conditions
- Obstructive Sleep Apnea
- Registration Number
- NCT02484222
- Lead Sponsor
- Children's Hospital of Fudan University
- Brief Summary
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested dosage of morphine postoperatively.
- Detailed Description
All the patients were intubated. Sevoflurane was used for maintenance without any opioids. Before the end of the procedure, spontaneous respiratory was recovered. All the patients were given 1 mcg/kg fentanyl i.v. after the end of the procedure. The positive result was defined as spontaneous respiratory rate decreased more than 50%, the others were defined as negative result. All the patients were given morphine for pain relief according to our protocol after extubation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
meet all of the following
- the American society of anesthesiologists (ASA) class Ⅰ ~ Ⅱ
- the age of 3 ~ 7 years old
- children who underwent selective adenotonsillectomy.
meet anyone of the following
- craniofacial malformations
- mental retardation
- BMI > 22 kg/m2
- a history of bronchial asthma
- a recent history of opioid use.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rescue Morphine Requirement average 1 hour from extubation
- Secondary Outcome Measures
Name Time Method Number of Participants With Pulse Oxygen Saturation Less Than 95 Percent average 1 hour from extubation Post-operative Nausea and Vomiting average 1 hour from extubation
Trial Locations
- Locations (1)
Chilren's Hospital of Fudan University
🇨🇳Shanghai, Shanghai, China