Community-based, Peer-delivered PrEP for Female Sex Workers in Rural Uganda: The Peers for PrEP (P4P) Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- HIV/AIDS
- Sponsor
- University of California, San Francisco
- Enrollment
- 140
- Locations
- 1
- Primary Endpoint
- Uptake of biomedical prevention
- Status
- Active, not recruiting
- Last Updated
- 9 months ago
Overview
Brief Summary
The overall goal of the P4P: Peers for PrEP (pre-exposure prophylaxis) study is to pilot test a peer-led and delivered intervention for biomedical HIV prevention that is tailored to women who engage in sex work in southwestern Uganda. This study will evaluate whether this intervention is feasible, acceptable, and increases uptake of biomedical prevention.
Detailed Description
The investigators have collaborated with key stakeholders to develop a community-based, peer-led intervention to provide biomedical prevention products (e.g. pre-exposure prophylaxis \[PrEP\] and post-exposure prophylaxis \[PEP\]) for women who engage in sex work in southwestern Uganda. A single-arm pilot trial will evaluate the feasibility, acceptability, and preliminary effectiveness of the intervention. The intervention is designed to reduce stigma associated with attending clinics (via community-based delivery by peers), leverage peer support to foster adherence, and reduce barriers to prevention services (through access to PrEP, HIV self-testing, and PEP from trusted peers).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Female sex at birth
- •Self-identified as commercial sex worker; exchange of sex for goods or money in last 3 months; or work or live in setting associated with sex work
- •Age \>=18 years (or mature minor \>=15 years)
- •HIV-negative by country-standard rapid testing algorithm
Exclusion Criteria
- •Contraindication to country-recommended PrEP regimen per national guidelines
- •Unable or unwilling to provide informed consent
- •Participation in another HIV prevention study
Outcomes
Primary Outcomes
Uptake of biomedical prevention
Time Frame: 6 months
Number of participants receiving biomedical prevention (e.g., oral pre-exposure prophylaxis \[PrEP\] or post-exposure prophylaxis \[PEP\]) divided by the number of participants
Secondary Outcomes
- Feasibility of delivery of the P4P intervention by peers(6 months)
- Acceptability of the P4P intervention(6 months)