Expression of HOXA10 and HOXA11 in the Endometrium of Infertility Patients With an Endometrial Polyp Before and After Polypectomy
Not Applicable
- Conditions
- Infertility
- Interventions
- Procedure: Endometrial biopsy
- Registration Number
- NCT02761278
- Lead Sponsor
- Hillel Yaffe Medical Center
- Brief Summary
The aim of this study is to measure the expression of HOXA10 and HOXA11 in the endometrium of infertility patients with an endometrial polyp before and after polypectomy. HOXA10 and HOXA11 are well-established markers of implantation. It is uncertain as to whether an endometrial polyp interferes with embryo implantation. A higher expression of HOXA10 and HOXA11 after polypectomy can indicate that endometrial polyp does interfere with embryo implantation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 20
Inclusion Criteria
- Infertile women with endometrial polyp
Exclusion Criteria
- Endometriosis
- Polycystic ovary syndrome
- Hydrosalpinx
- Sub-mucus myoma
- Women who have taken hormonal therapy in the preceding month
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description HOXA10 and HOXA11 Expression Before Polypectomy Endometrial biopsy A biopsy will taken in infertility patients with endometrial polyp before polypectomy HOXA10 and HOXA11 Expression After Polypectomy Endometrial biopsy A biopsy will taken in infertility patients with endometrial polyp 1-3 months after polypectomy
- Primary Outcome Measures
Name Time Method Comparison of amounts of HOXA10 and HOXA11 expressed before and after polypectomy Four months
- Secondary Outcome Measures
Name Time Method