MedPath

Screening for Delirium in Older Inpatients

Not Applicable
Completed
Conditions
Delirium in Old Age
Interventions
Diagnostic Test: Delirium Screening
Registration Number
NCT05690672
Lead Sponsor
Aalborg University Hospital
Brief Summary

Two-arm parallel-randomized pilot study and to collect data at the Department of Geriatric Medicine at Aalborg University Hospital. The aim is to assess the feasibility of a future randomized controlled study comparing Danish versions of 3D-CAM and 4AT in an acute medical setting. The primary objective is to assess 1) feasibility of obtaining informed consent and recruiting older adults within 24 hours of admission (or surgery) at the Department of Geriatric Medicine, Department of Acute Medicine, or Department of Orthopedic Surgery. Secondary objectives are 2a) to compare feasibility of recruitment and testing in the three different departments, 2b) to inform a preliminary evaluation of validity and reliability of the Danish version of screening instruments, and 2c) to obtain data on variance to support calculating sample size for a full-scale RCT.

Detailed Description

We will recruit participants through a consecutive sampling of all potentially eligible patients. Recruitment will take place in three different settings: the Department of Geriatric Medicine, the Department of Acute Medicine, and the Department of Orthopedic Surgery. One week will be allocated for recruitment in each setting.

Potentially delirious patients often have impaired cognitive status. Therefore, the process of recruitment and informed consent is critically important and poses a central issue of feasibility to be assessed in this study.

It cannot be known with certainty whether patients are delirious prior to inclusion into the study, and even among delirious patients, there are considerable circadian fluctuations (as this is a hallmark of the condition), meaning that patients may have lucid moments during the day where they are cognitively intact and may be able to give informed consent.

Generally, informed consent will be sought from participants when possible. In case they are permanently or temporarily unable to give informed consent, informed consent will be sought from next of kin. Due to the short time in the study for each participant, it is not anticipated that participants will regain the ability to give informed consent during the study. However, if they do, new informed consent will be obtained from the participant. The number of potential participants at each step will be documented to assess problems with feasibility.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Age over 80 years
  • Admission or surgery within the last 24 hours
Exclusion Criteria
  • Unable to obtain contact to next of kin for informed consent within time-frame

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
4AT screeningDelirium Screening-
3D-CAM screeningDelirium Screening-
Primary Outcome Measures
NameTimeMethod
Feasibility of recruitment overall3 weeks total

Measured by counting the number of participants giving informed consent, as well as number of participants in each setting not giving informed consent in each setting over the 3 week period.

Secondary Outcome Measures
NameTimeMethod
Validity of screening tools3 weeks total

Preliminary results of screening validity of 4A's test and 3D-CAM test comparing sensitivity and specificity

Feasibility of recruitment in different settings1 week each

Comparison of the number of participants (counted) recruited in the Department of Orthopedic Surgery, Geriatric Medicine and Acute Medicine

Trial Locations

Locations (1)

Aalborg University Hospital

🇩🇰

Aalborg, Northern Jutland, Denmark

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