Investigation of the role of cytokines, chemokines and their receptors in the inflammatory process in asthma patients

Recruiting

• Conditions: J45; Asthma

• Registration Number: DRKS00023843
• Lead Sponsor: niversitätsklinikum Erlangen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-17
• Results First Posted: 2022-12-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

healthy controls without Asthma or allergies in good general health condition. Asthmatic patients with and without immunotherapy with stable status of their Asthma bronchiale.

Exclusion Criteria

-severe, instable Asthma
-other chronic respiratory diseases except for allergic Rhinitis
-other chronic diseases or Long-term medication except for atopic eczema

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of this study is to have a better understanding of the regulatory role of cytokines, chemokines and their receptors in Asthma. They are often overexpressed in allergic Asthma. In cell culture Experiments PBMC are treated with different Stimuli and their gene Expression will be analyzed.

Secondary Outcome Measures

Name	Time	Method
The data from this study should be used to gain new approaches and targets for Asthma therapy.