The effect of ????Duloxetine with lansoprazole on the treatment of Gastroesophageal reflux disease

Phase 3

Recruiting

• Conditions: gastroesophageal reflux.; Gastro-esophageal reflux disease

• Registration Number: IRCT20141201020178N6
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

age between 18-65
Typical symptoms of Gastro -esophageal reflux disease (heartburn, regurgitation)and/ or endoscopic findings of Gastroesophageal reflux disease

Exclusion Criteria

Use of recent or previous anti-depressants and anti- anxiety drugs
A history of allergy to any of the medications
History of alcohol consumption
Atypical symptoms of Gastro esophageal reflux disease
Previous history of anxiety or depression
History of opium use
History of upper gastrointestinal disorders(Dyspepsia and/or Peptic ulcer disease)
History of cardiac , pulmonary , musculoskeletal disease and any malignancy.
History of medications such as: Sildenafil, calcium channel blocker, methylxanthine, nitrate and beta-agonist
Age under 18 years
Age older than sixty-five

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality and symptoms of patients with gastroesophageal reflux Disease. Timepoint: Before starting the intervention and 4 weeks later. Method of measurement: Patient Assessment of gastroesophageal re flux Quality of life and symptom Questionnaires.

Secondary Outcome Measures

Name	Time	Method
Adverse effect of medications. Timepoint: 2 and 4 weeks after starting the intervention. Method of measurement: Data gathering sheet of patients.