Effectiveness of the internet-based Unified Protocol mental health intervention for depression, anxiety, and related difficulties

Not Applicable

• Conditions: Depression, anxiety, and related disorders in a primary care setting; Mental and Behavioural Disorders; Depressive episode, Anxiety disorder, unspecified

• Registration Number: ISRCTN18056450
• Lead Sponsor: Trinity College Dublin

Brief Summary

2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36045387/ (added 01/09/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-13
• Last Update Posted: 21 August 2023
• Study Completion: 2025-05-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Minimum age 18 years old
2. Fluent in English
3. Have access to the Internet and an email account
4. Have symptoms of anxiety and/or depression referenced as primary presenting problem(s) on the referral form from the General Practitioner (GP)
5. A score of =8 on OASIS (Norma et al., 2006; Campbell-Sills et al., 2009) and/or a score of =8 on ODSIS (Bentley et al., 2014)

Exclusion Criteria

1. An increased risk of suicidality intent or ideation (at least moderate scores on the M.I.N.I. [see below about MINI] and/or a score > 2 on item 9 from the PHQ-9 [see below about PHQ-9]),
2. Psychotic disorder, manic or hypomanic episode, bipolar disorder, eating disorder, anti-social personality disorder and/or alcohol/substance use disorder as indicated by the M.I.N.I.
3. References to cognitive impairment on the referral form
4. Receipt of another psychological treatment at the start of the study

Pharmacological treatment during the treatment period will be allowed provided that it was stabilized 6 weeks prior to the start of being involved in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified