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Efficacy of oralTranexamicAcid in melasma

Phase 3
Recruiting
Conditions
Melasema.
Chloasma
Registration Number
IRCT20180111038311N1
Lead Sponsor
Ahvaz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
62
Inclusion Criteria

Patients with melasma with 18- 60 years old rang.

Exclusion Criteria

Patients with coagulopathy
Patients with thrombotic complications
Any of thrombotic events
Use of anticoagulant drugs or anti-platelet such as aspirin or Clopidogrel
Pregnancy, lactation, concomitant use of contraceptives,
The history of vitiligo or other pigmentation disorders,
Trancexamic Acid Sensitivity History
renal failure
History of treatment for melasma with clarifying drugs in 3 months before the start of the study.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pigmentation. Timepoint: MASIS record before intervention - one month and three months after intervention. Method of measurement: MASI Score.
Secondary Outcome Measures
NameTimeMethod
Gastrointestinal complications. Timepoint: before intervention - one month and three months after intervention. Method of measurement: Ask the patients.;Hypomenorea. Timepoint: before intervention - one month and three months after intervention. Method of measurement: ASk the patients.
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