Efficacy of vitB12 plus standard chronic HCV treatment versus standard chronic HCV treatment on sustained virologic response rate
Phase 3
- Conditions
- Chronic viral hepatitis C.Chronic viral hepatitis C
- Registration Number
- IRCT2015041720178N3
- Lead Sponsor
- Iran University of Medical Sciences,Rasoul Akram Hospital,Colorectal Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
naive HCV hepatitis patients that refer to Rasoul Akram Hospital,Gastroenterology Clinic.
Exclusion criteria:age<18 and age>70,previous treatment with interferon and/or ribavirin,concomitant causes of liver disease, such as HBV infection and autoimmune Hepatitis, alcohol user, HIV infection, hepatocellular carcinoma, decompensated cirrhosis, severe concurrent disease and contraindications to treatment including uncontrolled depression,psychosis, epilepsy, autoimmune diseases, poorlycontrolled hypertension, diabetes, heart failure and chronic obstructive pulmonary disease.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sustained virologic response rate. Timepoint: 24 weeks after treatment completion. Method of measurement: Quantitative HCV-PCR.
- Secondary Outcome Measures
Name Time Method