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Clinical Trials/ISRCTN12266984
ISRCTN12266984
Completed
未知

The IMpact of Vertical HIV infection on child and Adolescent Skeletal development in Harare (IMVASK) study

Biomedical Research and Training Institute0 sites600 target enrollmentJuly 22, 2019
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Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Biomedical Research and Training Institute
Enrollment
600
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2020 Protocol article in http://dx.doi.org/10.1136/bmjopen-2019-031792 (added 30/11/2021) 2022 Results article in https://doi.org/10.1002/jbmr.4752 (added 18/08/2023) 2023 Results article in https://doi.org/10.1097/QAD.0000000000003477 (added 18/08/2023) 2021 Results article in https://doi.org/10.1016/S2352-4642(21)00133-4 (added 18/08/2023)

Registry
who.int
Start Date
July 22, 2019
End Date
October 31, 2020
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Biomedical Research and Training Institute

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 8\-16 years (includes pre\- and peri\-pubertal children)
  • •2\. Living in Harare
  • •3\. With HIV only if:
  • •3\.1 Vertically\-acquired HIV and taking ART for at least two years (as adult studies demonstrate ART initiation is followed by an initial decline in BMD which stabilizes after 2 years)
  • •3\.2 The child is aware of their HIV status, to avoid inadvertent disclosure as a result of study participation

Exclusion Criteria

  • •1\. Acute illness (requiring immediate hospitalisation) and lack of consent

Outcomes

Primary Outcomes

Not specified

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