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Comparing neostigmine and metoclopramide on gastric residual volume

Phase 3
Recruiting
Conditions
dilatation of volume.
Acute dilatation of stomach
K31.0
Registration Number
IRCT20190804044432N1
Lead Sponsor
Zahedan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
100
Inclusion Criteria

Age between 20 and 50 years
Patients under mechanical ventilation
Patients with enteral nutrition through nasogastric tube

Exclusion Criteria

Previous use of beta blockers
Heart Block
Bradycardia (heart rate less than 60) before inclusion
Hypothermia in the form of central temperature below 35 degrees
Kidney Failure (CR> 1.5)
Use Erythromycin or Cisapride within 8 hours before starting the study
Recent surgery on stomach or digestive tract within the last ten days
Signs and symptoms of bowel obstruction
Pregnancy and lactation
Active bronchospasm
Extrapyramidal symptoms
Sensitivity to Neostigmine
Active gastrointestinal bleeding

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Gastric residual volume. Timepoint: Before starting the drug infusion and 3, 6, 9 and 12 hours after the start of the infusion. Method of measurement: Aspirate with a gavage syringe.
Secondary Outcome Measures
NameTimeMethod
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