Implementation and Effects of Pulse-contour-automated SVV/CI Guided Goal Directed Fluid Therapy Algorithm for the Routine Management of Major Abdominal Surgery Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Length of stay in hospital
研究概览
简要总结
This study examines the effect of an algorithm for GDT for patients undergoing major surgery under routine conditions.
详细描述
Goal directed fluid management in major abdominal surgery has been shown to reduce perioperative complications. The approach aims to optimize the intravascular fluid volume by use of minimally invasive devices which calculate flow-directed variables such as stroke volume (SV) and stroke volume variation (SVV). The investigators aim to show the feasibility of routinely implementing such hemodynamic monitoring during major abdominal surgery, and to evaluate its effects in terms of perioperative fluid management and postoperative outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pancreatic surgery
- •colorectal surgery
排除标准
- •admission for revisional surgery
结局指标
主要结局
Length of stay in hospital
时间窗: 90 days
次要结局
- Pneumonia(90 days)
- ACS(90 days)
- acute renal failure(90 days)
- Sepsis(90 days)
- Intraabd. Infection(90 days)
- wound infection(90 days)
- UTI(90 days)
- intraoperative crystalloid volume(1 day)
- intraoperative colloid volume(1 day)
- Length of stay at ICU(90 days)
- Total amount of complications per patient(90 days)
- Insufficiance of bowel anastomosis(90 days)
研究者
Dr. Thomas Kratz
MD
Philipps University Marburg Medical Center