Fundus Autofluorescence After Vitrectomy for Epiretinal Membrane

Completed

• Conditions: Epiretinal Membrane

• Registration Number: NCT02628158
• Lead Sponsor: Kyorin University

Brief Summary

Fundus autofluorescence (FAF) at the macula originates from hyperfluorescence from retinal pigment epithelium (RPE) and blockage of hyperfluorescence by macular pigment. Investigators evaluate whether presence of FAF may correlate to the postoperative visual outcome for epiretinal membrane.

Detailed Description

92 eyes with epiretinal membrane were performed vitreous surgery, epiretinal membrane removal and internal limiting membrane (ILM) peeling. Presence of hyperfluorescence in FAF at the macular area and best-corrected visual acuity (BCVA) was evaluated preoperatively and at postoperative 1, 3, and 6 months with ultra-wide angle imaging.

Study Timeline

• Study Start: 2013-04
• Primary Completion: 2015-04
• Study Completion: 2015-10
• Status Verified: 2015-12
• Study First Submitted: 2015-12-06
• Study First Submitted QC: 2015-12-08
• Last Update Submitted: 2015-12-08
• Study First Posted: 2015-12-11
• Last Update Posted: 2015-12-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Not specified
• Target Recruitment: 91

Inclusion Criteria

• The inclusion criteria were patients who underwent vitrectomy and internal limiting membrane removal for epiretinal membrane and had followed for more than 6 months.

Exclusion Criteria

• The patients with follow-up less than 6 months.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual acuity before and after surgery	Changes from baseline to 1, 3, 6 months	Vision

Secondary Outcome Measures

Name	Time	Method
Presence of fluids autofluorescence at the macular area	Changes from baseline up to 6 months	Fundus autofluorescence

Trial Locations

Locations (1)

Kyorin Eye Center; 🇯🇵 Mitaka, Tokyo, Japan