Efficacy of a herbal syrup containing Lavander and Chinese dodder in the treatment of Major Depressive Disorder, with anxious distress

Not Applicable

• Conditions: Depressive episode.; Mild depressive episode

• Registration Number: IRCT2016102430459N1
• Lead Sponsor: Vice Chancellor for research, School of Traditional Medicine, Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Age between 18 to 60 years old
2. Presence of Major Depressive Disorder, with anxious distress based on DSM-5 criteria
3. Scores lower than 18 in the Hamilton Rating Scale for Depression.
4. Scores lower than 24 in the Hamilton Rating Scale for Anxiety

Exclusion criteria:
1. The presence of psychotic symptoms, current or past history of Bipolar disorder, Schizophrenia and Schizotypal personality disorder
2. Receiving psychotropic medications or any antidepressants during the past 14 days
3. The presence of an unstable disorder, Kidney or Liver failure, malignancy, Thyroid problems, Diabetes, past history of Epilepsy, bleeding disorders
4. Nursing and pregnant women, reproductive age without a contraception method
5. Substance abuse or addiction in the past 3 months
6. Suicidal tendency in the past year, scores greater than 2 on the Suicide item of the Hamilton Rating Scale for Depression
7. Women who are receiving OCP
8. Any clinically significant deterioration in the condition of the subject from baseline detected by the attending physician
9. Current or past history of Cognitive disorder in the past year
10. ECT during the past 3 months
11. Psychotherapy in the past month
12. A past history of allergy towards Lavender, Chinese dodder and Citalopram

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of depression. Timepoint: Baseline, weeks 3 and 6 after starting treatment. Method of measurement: Hamilton Depression Rating Scale.

Secondary Outcome Measures

Name	Time	Method
Anxiety. Timepoint: Baseline, weeks 3 and 6 after starting treatment. Method of measurement: Hamilton Anxiety Rating Scale.