ew tumor marker for early detection of hepatocellular carcinoma (HCC)
- Conditions
- Apply to basic benefits in screening people at high risk of liver cell cancer at the national levelPIVKA-IIAFP-L3
- Registration Number
- TCTR20200313001
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 1080
1. Patients aged 18 years and older
2. The annual health check-up who has regular blood tests including high frequency sound tests and no lumps suspected of primary liver cancer
3. Chronic hepatitis B patients Males aged over 40 years and females aged over 50 or have direct relatives with primary liver cancer
4.Chronic hepatitis C patients with pathological effects of liver tissue With at least level 3 fascia Or the flexibility of the liver with transient elastography greater than or equal to 9.5 or blood Fibrotest® is greater than 0.58 regardless of whether it has been treated or not.
5. Patients who have been diagnosed with liver cirrhosis for any reason From the examination of high frequency sound waves Radiographic images using a computer or an X-ray of the upper abdomen.
6. Patients who have detected a lump in the liver greater than or equal to 1 cm in size from the ultrasound Radiographic images using a computer or an X-ray of the upper abdomen.
1. pregnant patients
2. Patients with jaundice from biliary tract obstruction
3. Patients who received vitamin K during the study
4. Patients receiving warfarin While studying
5. Other types of cancer detected While diagnosing primary liver cancer
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary liver cancer diagnosis 3 year PIVKA-II Test µTASWako i30, ELECSYS, ARCHITECT AFP-L3
- Secondary Outcome Measures
Name Time Method /A N/A N/A