Effect of alpha-lipoic acid supplement in rheumatoid arthritis
- Conditions
- Rheumatoid Arthritis.Rheumatoid arthritis, unspecified
- Registration Number
- IRCT201205263140N5
- Lead Sponsor
- Research Vice-chancellor of Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
female rheumatoid arthritis patients who have ACR criteria 1987 for RA; Age range of 20 to 50 years; disease activity score-28< 5.1; not changing the treatment protocol since 2 months before the study, not receiving antioxidant or anti inflammatory supplements since 1 month before the study; desire to attend in study and signing the informed consent form. Exclusion criteria: pregnancy; lactation; post menopause; receiving hormone replacement therapy; receiving oral contraceptive pill; smoking or being a passive smoker; presence of cancer; diabetes mellitus; hormonal dysfunctions; under nutrition; severe obesity (BMI>40), uncontrolled hypertension; renal failure and hepatic diseases; digestive disorders; other autoimmune and/or inflammatory disease; changing treatment protocol and lifestyle during the study; receiving antioxidant or anti-inflammatory supplements during the study; acceptance rate<75% and unwillingness to continue the study.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method