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Early Feeding After A Cesarean Delivery Hastens Recovery Time for Bowel Function

Not Applicable
Completed
Conditions
Gastrointestinal Disorders, Functional
Interventions
Other: Regular diet within 6hrs postoperative
Registration Number
NCT02396485
Lead Sponsor
The University of Texas Medical Branch, Galveston
Brief Summary

After institutional review approval, pregnant women that are scheduled for elective cesarean delivery will be approached for participation in the study. The study informed consent will be obtained. The study's time frame inclusive will be from 2013 till 2016.

Patients will be randomized to regular diet within 6 hrs postoperative (Early group) versus remaining nothing per os (NPO, i.e nothing per mouth) for 12hrs, and the diet then advanced as tolerated after 12hrs (Routine Group) as standard postoperative protocol in the investigators' institution.

Primary outcome will be time to pass flatus. Secondary outcomes will include hospital length of stay, postoperative nausea, vomiting and patient satisfaction. Randomization will be performed using a computer generated random list of numbers assigning patients to the 2 groups of the study. This list of random number assignments will be kept secure in an opaque envelope until the end of the study. Patients in the Early group will be started on regular diet within 6 hrs of surgery, whereas the routine group patients will be kept strict NPO 12hrs, and clear liquid diet will be started after 12hrs. Diet will be advanced as tolerated, i.e. if clears were tolerated or flatus or bowel movement occurred, patients will be started on solid foods. If diet not tolerated, a full liquid diet will be given instead. Consequently if patient tolerated full liquid diet, a regular diet will be then initiated. Patients will be discharged home only if they tolerate solid food with absence of emesis, have flatus or bowel movement. Time Zero is defined as time of skin incision.

Detailed Description

After institutional review approval, pregnant women that are scheduled for elective cesarean delivery will be approached by Principal investigator or any of the co-investigators for participation in the study during the the preoperative visit which coincides with the same day of scheduled cesarean in a private patient room. . Prospective subjects will be presenting for their preoperative appointment (same day of scheduled cesarean delivery) in labor and delivery and will be asked to participate in the study. The study will be explained as in the consent form and if agreed patients will elect either to or not to participate in the study after all risks and benefits are explained. Data to be collected will consist of time in minutes of passing flatus, time in minutes of having a bowel movement, hospital length of stay, postoperative nausea, vomiting and presence of ileus (unable to tolerate diet, abdominal distention, no bowel movement nor flatus, abdominal x-ray demonstrating air/fluid levels in bowel). Patients will be contacted once to twice a day for assessment of data points mentioned above. If elected to participate consents will be obtained. Randomization will be done at time of consents. The study's time frame inclusive will be from 2013 till 2016.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
177
Inclusion Criteria
  • Gravid women greater than 37 weeks undergoing elective cesarean delivery.
Exclusion Criteria
  • Intra-operative bowel surgery
  • Preeclampsia requiring magnesium sulfate
  • Diabetes Mellitus.
  • Planned secondary closure of the skin incision
  • Any gastrointestinal and/or medical conditions that precludes early consumption of solid food
  • General anesthesia
  • Gestational age less than 37 weeks.
  • Patients who are mentally incapacitated or decisionally impaired.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Early Feeding ArmRegular diet within 6hrs postoperativePatients will be started on regular diet within 6 hrs postoperative.
Primary Outcome Measures
NameTimeMethod
Passing Flatusparticipants will be followed for the duration of hospital stay, an expected average of 2-5 days

The primary outcome is the duration in minutes from surgery completion(skin closure) and time of passage of first flatus (passing gas per anus).

Secondary Outcome Measures
NameTimeMethod
Bowel Evacuationparticipants will be followed for the duration of hospital stay, an expected average of 2-5 days

First time in minutes from completion of surgery that patient reports passing bowel movement or stools.

Bowel soundsparticipants will be followed for the duration of hospital stay, an expected average of 2-5 days

First time in minutes from completion of surgery that bowel sounds are heard active.

Nausea or vomitingparticipants will be followed for the duration of hospital stay, an expected average of 2-5 days

First time in minutes from completion of surgery that patient reports nauseated or has actually had emesis.

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