The Use of Nasopharyngeal Airway as an Alternative to Laryngeal Mask Airway to Maintain Anaesthesia in Patients Undergoing Four-Lids Blepharoplasty
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 148
- Locations
- 1
- Primary Endpoint
- Incidence of postoperative soar throat
Study Overview
Brief Summary
General anaesthesia demands securing patient's airway either with endotracheal tube or laryngeal mask (LMA); however, both carry the disadvantage of postoperative soar throat. Nasopharyngeal airway (NPA) can be an alternative without the risk of postoperative soar throat.6 The primary end point of our study is to assess the incidence of soar throat with the use of NPA compared to LMA in patients receiving general anaesthesia during blepharoplasty.
Detailed Description
After approval of medical ethical committee at Ain-Shams University and obtaining written informed consent, 148 adult ASA II-III patients aged between 40 and 60 years old admitted to Ain-Shams university hospitals for blepharoplasty will be enrolled in this study.
Patients will then be randomly and evenly divided into two equal groups (74 patients each) using computer-generated list:
Group N: Patients' nasal mucosa will be anaesthetized and vasoconstricted. K-Y gel will be applied to the tip of nasopharyngeal airway (NPA) of appropriate size. The NPA will then be advanced into the dominant nostril along the septum horizontally.
Group L: K-Y gel will be applied to the tip of the laryngeal mask (LMA) of appropriate size. The LMA will be introduced along the hard palate towards the hypopharynx until resistance is felt.
Anaesthesia will be maintained by sevoflurane 3-4% and propofol infusion 0.5-1 mg.kg-1.hr-1.All patients will receive local infiltration anaesthesia given by the surgeon.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Triple (Participant, Care Provider, Outcomes Assessor)
Eligibility Criteria
- Ages
- 40 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •consented patients, age: 40-60 years old, ASA II-III
Exclusion Criteria
- •Uncontrolled hypertension (systolic blood pressure > 160 mmHg) or ischaemic heart disease.
- •Pre-existing coagulation defects or anticoagulation medication.
- •Renal impairment.
- •Recent upper respiratory tract infections, asthma, chronic obstructive pulmonary disease, and smoking.
- •History of obstructive sleep apnea.
- •Chronic drug or alcohol abuse.
- •Morbid obesity; BMI >40 or BMI >35 and experiencing obesity-related health conditions, such as high blood pressure or diabetes.
- •Allergy to any of the drugs used in the study.
Arms & Interventions
Group N
Patients' nasal mucosa will be anaesthetized and vasoconstricted. K-Y gel will be applied to the tip of nasopharyngeal airway (NPA) of appropriate size. The NPA will then be advanced into the dominant nostril along the septum horizontally.
Intervention: Nasopharyngeal airway or laryngeal mask airway (Device)
Group L
K-Y gel will be applied to the tip of the laryngeal mask (LMA) of appropriate size. The LMA will be introduced along the hard palate towards the hypopharynx until resistance is felt.
Intervention: Nasopharyngeal airway or laryngeal mask airway (Device)
Outcomes
Primary Outcomes
Incidence of postoperative soar throat
Time Frame: 2-4 hours postoperative
presence or abscence of soar throat
Secondary Outcomes
No secondary outcomes reported
Investigators
Hala Salah El-Din El-Ozairy
Lecturer of Anaesthesia, ICU and Pain management, Faculty of Medicine, Ain Shams University
Ain Shams University