Postoperative Complications After Appendectomy

Completed

• Conditions: Appendicitis

• Registration Number: NCT03119740
• Lead Sponsor: Kepler University Hospital

Brief Summary

The frequency of complications after appendectomy is about 9% . The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

Detailed Description

Background: Acute appendicitis is a common emergency in general surgery. The frequency of complications after appendectomy is about 9% \[9\]. The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

Methods: This retrospective single-center cohort study comprised 744 patients who had undergone open or laparoscopic appendectomy for clinically suspected appendicitis between 1 January 2011 and 31 December 2015 at the department of general and visceral surgery, Kepler University Hospital in Linz, Austria. Demographic data, the surgical technique, postoperative complications, histopathological findings, postoperative white blood counts, and C-reactive protein levels were evaluated.

Study Timeline

• Study Start: 2016-08-01
• Primary Completion: 2016-10-30
• Study Completion: 2016-11-30
• Study First Submitted: 2017-04-11
• Study First Submitted QC: 2017-04-13
• Study First Posted: 2017-04-19
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-03
• Last Update Posted: 2023-10-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 744

Inclusion Criteria

• clinically suspected appendicitis between 1 January 2011 and 31 December 2015

Exclusion Criteria

• an elective appendectomy as part of an oncological or gynecological operation tumor was found intraoperatively and required ileocecal resection or right hemicolectomy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
superficial wound infection	4 weeks postoperative	superficial wound infection in open and laparoscopic appendectomy

Secondary Outcome Measures

Name	Time	Method
intraabdominal abscess	4 weeks postoperative	intraabdominal abscess in open and laparoscopic appendectomy
ileus	4 weeks postoperative	ileus in open and laparoscopic appendectomy

Trial Locations

Locations (1)

Clinic for General and Visceral Surgery, Kepler University Clinic Linz; 🇦🇹 Linz, Upper Austria, Austria