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Biomarkers in Prediction of AMI

Not Applicable
Recruiting
Conditions
Acute Mesenteric Ischemia
Interventions
Diagnostic Test: Sequential blood samples
Registration Number
NCT06212921
Lead Sponsor
University of Tartu
Brief Summary

Current study will be undertaken to identify combinations of biomarkers that can reliably identify acute mesenteric ischaemia (AMI) and distinguish between non-transmural and transmural ischaemia. Different combinations of biomarkers for different sub-types and severity of AMI, and different time points of measurement after onset of symptoms.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
250
Inclusion Criteria
  • Age 18 years or older
  • Initial decision in favour of further diagnostics of mesenteric ischaemia
Exclusion Criteria
  • Age <18 years
  • Consent declined by patient or next of kin (delayed consent)
  • Chronic mesenteric ischaemia without an acute event
  • Immediate decision for withdrawal of further diagnostics and active treatment
  • Referral from another hospital with already established diagnosis of AMI
  • AMI diagnosed at surgery without previously having been considered

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Patient with suspicion of acute mesenteric ischaemiaSequential blood samplesBolld samples is the only intervention. All patients with suspicion of AMI will be included and blood samples collected
Primary Outcome Measures
NameTimeMethod
Rate of correctly predicted cases of acute mesenteric ischaemia10 months

Rate of correctly predicted cases of Acute mesenteric ischaemia using different biomarkers

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Tartu University Hospital

🇪🇪

Tartu, Estonia

Lucerne Cantonal Hospital

🇨🇭

Luzern, Switzerland

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