Comparison of the Effectiveness of dexmedetomidine and propofol in electrochemotherapy of breast cancer skin lesio

Phase 2

Recruiting

• Conditions: breast cancer skin lesion.; Secondary malignant neoplasm of skin; C79.2

• Registration Number: IRCT20240515061805N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Symptomatic metastatic skin lesions (like bleeding, exudation, smell or ulceration)
development of skin metastases, in which the symptoms mentioned can be expected
Patients who receive systemic treatment and have a good effect on their primary cancer, but their skin lesions do not respond to these treatments or are progressing
patients preferring electrochemistry
multiple skin lesions or a lesion larger than 1 cm
ASA group II, I, III
patients between 18 and 60 years old

Exclusion Criteria

Pregnancy and breastfeeding
Allergy to any of the drugs used in the study
hypertension
impaired liver and kidney function
Hereditary heart diseases
ischemic heart disease,
smoking
using beta blockers and sedative drugs
refusing to sign an informed consent form

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of patient recovery time with Aldrete score based on assessment of vital signs and consciousness. Timepoint: after operation. Method of measurement: Aldrete score.;Neuropathic pain scale. Timepoint: before and after operation. Method of measurement: neuropathic pain scale.;Ramsay sedation scale. Timepoint: before, during and after operation. Method of measurement: Ramsay sedation scale.;Bispectral index. Timepoint: during operation. Method of measurement: Bispectral index sensor.