Effect van lage dosis radiotherapie bij pijn bij milde heupartrose
Recruiting
- Conditions
- Patients with Painful, low-grade* osteoarthritis of the hip who present themselves at the orthopedic outpatient clinic of Orbis Medisch Centrum·
- Registration Number
- NL-OMON24950
- Lead Sponsor
- dr E.J.P. JansenOrthopedic surgeonAtrium-Orbis MCSittard-Geleen
- Brief Summary
A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
· Painful, low-grade* osteoarthritis of the hip
· Above 50 years old
· Synovitis confirmed with ultrasound imaging
· Ability and willingness to follow instructions and to return for follow-up
evaluations
*: Kellgren-Lawrence grade I-II
Exclusion Criteria
· Patients diagnosed with reumathoid arthritis
· Patients with osseous metastasis
· Patients with rheumatoid factor > 20 kU/l or blood sedimentation rate > 20mm
· Patients with a moderate or severe osteoarthritis grade**
· Patients with a hip/spine dilemma
· Prostethic implant in the affected joint
· Not able or willing to undergo bone scintigraphy or blood sampling
**: Kellgren-Lawrence grade III-IV
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the effect of LDRT on pain sensation after 1,2,3,6 months in<br>early osteoarthritis of the hip, measured with a Visual Analogue Scale (VAS),<br>compared to placebo 'sham' irradiation and standard-of-care conservative<br>treatment.
- Secondary Outcome Measures
Name Time Method · To determine the effect of LDRT on patient reported outcome measures<br>(PROM) including WOMAC and Oxford Hip Score.<br>· To determine the effect of LDRT on quality of life, assessed with the EuroQoL-<br>5D questionnaire.<br>· To investigate the relationship between effect of LDRT and level of synovitis,<br>measured through ultrasound, bone scintigraphy and blood BSE level.