Investigating the effectiveness of Alovera spray on diabetic foot ulcers
Phase 3
Recruiting
- Conditions
- E11.4Diabetic Foot Ulcers.Type 2 diabetes mellitus with neurological complications
- Registration Number
- IRCT20080904001199N7
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
Patients with diabetic neuropathic and neuroischemic foot ulcers
PEDIS Grade 1&2 Diabetic Foot Ulcer
Wagner Grade 1, 2 and 3 Diabetic Foot Ulcer
Exclusion Criteria
Getting infected with Covid-19
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Wound area. Timepoint: Before the intervention - the first week after the intervention - the second week after the intervention - the third week after the intervention - the fourth week after the intervention - the fifth week after the intervention. Method of measurement: Using a ruler and ImageJ software.;The bacterial load on the wound surface. Timepoint: Before the intervention - the second week after the intervention - the fifth week after the intervention. Method of measurement: Microbial culture will be done using swap and agar medium.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Alovera spray's effect on diabetic foot ulcer healing in type 2 diabetes patients with neuropathy?
How does Alovera spray compare to standard-of-care treatments like silver sulfadiazine in promoting wound closure for diabetic foot ulcers?
Are there specific biomarkers that could identify type 2 diabetes patients most likely to benefit from Alovera spray therapy for foot ulcers?
What are the potential adverse events associated with Alovera spray application on chronic wounds in diabetic patients with neurological complications?
How does Alovera spray's efficacy in diabetic foot ulcer management compare to other natural compounds like honey or curcumin-based treatments?