Observational Study and follow up of a Sepsis Biomarker for Sepsis Diagnosis in the Intensive Care

Not Applicable

• Conditions: Sepsis; Diabetes; Infection - Other infectious diseases

• Registration Number: ACTRN12609000576224
• Lead Sponsor: Intensive Care Unit, Christchurch Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-07-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Critically ill patients who are on the SPRINT glycaemic control protocol age >=16 years

Exclusion Criteria

Moribund or not expected to live for longer than 72 hours. Anticipated stay in ICU<=48 hrs.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between model-based and biological based sepsis biomarker and the <br>severity of sepsis. The correlation will be calculated using a bivariate method. In addition, operating receiver characteristic (ROC) curve will be used to assess the sensitivity and specificity of the biomarkers.[baseline, T=0 hr when suspected sepsis and/or Systemic Inflammatory Response Score (SIRS)>=3, T=12 hrs, T=24 hrs, T=48 hrs and time of recovery.]

Secondary Outcome Measures

Name	Time	Method
Incidence of diabetes in patients who develop hyperglycaemia during their Intensive Care Unit (ICU) stay[2, 5 and 10 years after patient's stay in ICU]