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The Effect of a Smartphone-assisted Hybrid Cardiac Rehabilitation Program in Patients With Heart Failure.

Not Applicable
Recruiting
Conditions
Heart Failure
Interventions
Other: smartphone-assisted hybrid cardiac rehabilitation (SHCR)
Registration Number
NCT05873543
Lead Sponsor
National Taiwan University Hospital
Brief Summary

The aim of this randomized controlled trial is to compare the impact of a case manager-led smartphone-assisted hybrid cardiac rehabilitation program with usual care in patients with HF. Participants will undergo a 12-week program led by a case manager and assisted by a smartphone. The study aims to answer two main questions:

1. Is the novel cardiac rehabilitation model feasible for patients with HF?

2. Does the intervention group show a significant improvement in exercise capacity and adherence compared to the usual care group?

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Patients with heart failure between the ages of 18 and 80 years old.
  • NYHA (New York Heart Association) functional classification of 1 to 3.
  • Patients must be in a stable condition and under outpatient follow-up.
Exclusion Criteria
  • Patients who have contraindications for exercise according to the American College of Sports Medicine's Guidelines for Exercise Testing and Prescription.
  • Patients who are unable to complete cardiopulmonary exercise testing.
  • Patients who are unable to follow verbal instructions.
  • Patients who are unable to walk independently or pedal a stationary bicycle.
  • Patients who are unable to use communication app on a smartphone.
  • Patients who already engage in physical activity exceeding the recommended moderate intensity of 150 minutes per week or are currently participating in cardiac rehabilitation.
  • Patients who do not provide consent to participate in the trial.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
smartphone-assisted hybrid cardiac rehabilitation (SHCR)smartphone-assisted hybrid cardiac rehabilitation (SHCR)Participants receive a 12-wk case manager-led smartphone-assisted hybrid cardiac rehabilitation with follow-up at 12 week and 6 months.
Primary Outcome Measures
NameTimeMethod
Change of peak oxygen uptakeat baseline, 12 weeks(post-intervention), and 6 months.

Peak oxygen uptake will be assessed using cardiopulmonary exercise test before intervention, at 12 weeks (post-intervention), and at 6 months.

Change of 6 minute walking testat baseline, 12 weeks(post-intervention), and 6 months.

6 minute walking test will be performed before intervention, at 12 weeks (post-intervention), and at 6 months.

Secondary Outcome Measures
NameTimeMethod
Adherence to prescribed exercise12 weeks(post-intervention)

We will evaluate the percentage of completed prescribed exercises at 12 weeks.

Depressionat baseline, 12 weeks(post-intervention), and 6 months.

The investigators will assess the change in Patient Health Questionnaire (PHQ-9). The PHQ-9 score ranges from 0-27. Higher scores indicate worsen symptoms.

Blood test: Triglycerideat baseline, 12 weeks(post-intervention), and 6 months.

The Triglyceride will be tested in the laboratory.

Evaluation of Quality of lifeat baseline, 12 weeks(post-intervention), and 6 months.

The investigators will assess the change in 36-Item Short Form Survey(SF-36).

Evaluation of physical activityat baseline, 12 weeks(post-intervention), and 6 months.

The investigators will assess the change in physical activity using International Physical Activity Questionnaire(IPAQ) Taiwan version.

Anxietyat baseline, 12 weeks(post-intervention), and 6 months.

The investigators will assess the change in Generalized Anxiety Disorder scale (GAD-7). The GAD-7 score ranges 0-21. Higher scores indicate worsen symptoms.

Evaluation of grip strengthat baseline, 12 weeks(post-intervention), and 6 months.

The grip strength will be measured using a grip goniometer with the participants seated and the elbow flexed at 90 degrees.

Blood test: HDLat baseline, 12 weeks(post-intervention), and 6 months.

The HDL will be tested in the laboratory.

Evaluation of frailtyat baseline, 12 weeks(post-intervention), and 6 months.

The investigators will evaluate the change in the Clinical Frailty Scale, which ranges from 1 to 9. Higher scores represent greater illness.

Blood test: Total cholesterolat baseline, 12 weeks(post-intervention), and 6 months.

The Total cholesterol will be tested in the laboratory.

Blood test: LDLat baseline, 12 weeks(post-intervention), and 6 months.

The LDL will be tested in the laboratory.

Blood test: NT-proBNPat baseline, 12 weeks(post-intervention), and 6 months.

The NT-proBNP will be tested in the laboratory.

Trial Locations

Locations (1)

Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital

🇨🇳

Taipei, Taiwan

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