Effect of Glucose-Insulin-Potassium on patients with Acute ST-Segment-Elevation Myocardial Infarctio
Phase 2
- Conditions
- Patients with ST elevation myocardial infarction.Acute myocardial infarction
- Registration Number
- IRCT138804302210N1
- Lead Sponsor
- Sabzevar university of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Inclusion:All consecutive patients who had 20 minutes chest pain or its equivalent, time from symptom onset <12 hours, and had ST elevation =1 mm in =2 contiguous electrocardiographic leads when admitted to the Coronary Care Unit of the vaseie general hospital (Sabzevar ,Iran) were recruited.
Exclusion: Patient with systemic infection, glucocorticoid therapy, hypo tension, congestive heart failure, creatinine >2.0 mg/dL and anemia (hemoglobin <11 g/dL), were excluded. Further exclusion criteria were unwillingness to participate.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma CRP level in the control and GIK groups. Timepoint: 0, 6, 24 and 48 hours after admission. Method of measurement: ELIZA kit.
- Secondary Outcome Measures
Name Time Method Plasma CK and CK-MB and cardiac troponin I concentrations. Timepoint: 0, 16 and 24 hours after admission. Method of measurement: ELIZA kit.;ST-segment resolution. Timepoint: 60 minutes after thrombolytic therapy. Method of measurement: ECG.;Pain. Timepoint: 0,1 and 2 hours after thrombolytic therapy. Method of measurement: Interview.;Arrythmia. Timepoint: 7 days after admission. Method of measurement: Cardiac monitoring by a physician.;Re infarction. Timepoint: 7 days after admission. Method of measurement: Recurrent ST elevation of 0.1 mv or recurrent increase in creatinin kinase MB.;Mortality. Timepoint: 7 days after admission. Method of measurement: Any death when cardiac death could not be excluded.;Ejection fraction. Timepoint: 72 hours after admission. Method of measurement: Echocardiography.