Epidemiological and Clinical Characteristics of COVID-19 Patients in Kazakhstan in Early 2020: a Retrospective, Observational Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Covid19
- Sponsor
- Semey State Medical University
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Clinical and demographic predictors of disease severity among hospitalized COVID-19 patients.
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of this study is to assess the epidemiological and clinical features of patients diagnosed with COVID-19 in Kazakhstan at the onset of the pandemic.
Detailed Description
There is a paucity of data available on the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) in Kazakhstan. While a global effort in search for effective treatments and vaccines against COVID-19 is in effect, it is important that high quality and up-to-date information be available from a broad variety of populations on the dynamics of infection. This is especially important in regions where, due to resource shortage, epidemiologic surveillance may have gaps. To address the current gaps, medical records will be obtained for patients with confirmed COVID-19 during the first months of the pandemic (February-April 2020). The epidemiologic and clinical features including the demographics, clinical manifestation, laboratory parameters, radiologic assessments and clinical outcomes will be analyzed. The results of this study will facilitate the clinical management of COVID-19 patients in Kazakhstan and ultimately inform the ongoing efforts to curb the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the region.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Laboratory confirmation of SARS-CoV-2 infection by polymerase chain reaction.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Clinical and demographic predictors of disease severity among hospitalized COVID-19 patients.
Time Frame: approximately 70 days
Risk factors associated with disease severity and their odds ratios (ORs) will be assessed by the univariable and multivariable logistic regression models.
Clinical and demographic predictors of mortality among hospitalized COVID-19 patients.
Time Frame: approximately 70 days
Risk factors associated with death and their odds ratios (ORs) will be assessed by the univariable and multivariable logistic regression models.